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This document – based on the deliberations of the WHO meeting, highlights some of the basic issues in the field of prevention and promotion in mental health with special reference to the evidence-base. It also outlines the role of WHO in advancing current knowledge and disseminating information among Member States, especially among developing countries. It is hoped that the information given here will assist in wider utilization of appropriate and effective interventions on prevention and promotion towards reducing the burden of mental disorders and in enhancing the mental health of populations.